Intravenous lipid emulsion for local anesthetic toxicity: A review of the literature
نویسندگان
چکیده
منابع مشابه
Intravenous lipid emulsion for treatment of local anesthetic toxicity
CLINICAL QUESTION Is intravenous lipid emulsion a safe and effective therapy for the reversal and treatment of local anesthetic toxicity? RESULTS Systematic reviews, human case reports, and experimental animal studies have demonstrated the efficacy of intravenous lipid emulsion therapy in successfully reversing cardiac arrhythmias, cardiac arrest, and cardiac collapse seen with severe systemi...
متن کاملSystematic review of the effect of intravenous lipid emulsion therapy for local anesthetic toxicity.
BACKGROUND Following national and regional recommendations, intravenous lipid emulsion (ILE) has become established in clinical practice as a treatment for acute local anesthetic (LA) toxicity, although evidence of efficacy is limited to animal studies and human case reports. A collaborative lipid emulsion workgroup was therefore established by the American Academy of Clinical Toxicology to rev...
متن کاملLipid Emulsion for Local Anesthetic Systemic Toxicity
The accidental overdose of local anesthetics may prove fatal. The commonly used amide local anesthetics have varying adverse effects on the myocardium, and beyond a certain dose all are capable of causing death. Local anesthetics are the most frequently used drugs amongst anesthetists and although uncommon, local anaesthetic systemic toxicity accounts for a high proportion of mortality, with lo...
متن کاملSystematic review of the effect of intravenous lipid emulsion therapy for non-local anesthetics toxicity.
BACKGROUND The use of intravenous lipid emulsion (ILE) therapy for the treatment of lipophilic drug toxicity is increasing. Despite this, the evidence for its effect in non-local anesthetic toxicity remains sparse. Furthermore, many case reports describe ILE use for substances in which no clear efficacy data exists. The American Academy of Clinical Toxicology established a lipid emulsion workgr...
متن کاملLipid infusion as a treatment for local anesthetic toxicity: a literature review.
Local anesthetic toxicity can have catastrophic outcome in an otherwise benign procedure. Introduction of even a small amount of local anesthetic into the bloodstream can cause cardiac arrest in a healthy patient. Most healthcare facilities rely on standard resuscitative techniques to treat such events; however, treatment via infusion of lipid emulsion has been used successfully to stabilize th...
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ژورنال
عنوان ژورنال: Journal of Medical Toxicology
سال: 2008
ISSN: 1556-9039,1937-6995
DOI: 10.1007/bf03161199